Biotransformation and molecular docking studies of aromatase inhibitors
نویسندگان
چکیده
منابع مشابه
Molecular Docking of Aromatase Inhibitors
Aromatase is an enzyme that plays a critical role in the development of estrogen receptor positive breast cancer. As aromatase catalyzes the aromatization of androstenedione to estrone, a naturally occurring estrogen, it is a promising drug target for therapeutic management. The undesirable effects found in aromatase inhibitors (AIs) that are in clinical use necessitate the discovery of novel A...
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ژورنال
عنوان ژورنال: Steroids
سال: 2016
ISSN: 0039-128X
DOI: 10.1016/j.steroids.2016.07.003